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Slitrk gene duplication and expression in the developing zebrafish nervous system
Authors:Jennifer Round  Brittany Ross  Mark Angel  Kayla Shields  Barbara Lom
Institution:Department of Biology and Program in Neuroscience, Davidson College, Davidson, North Carolina
Abstract:Results : As a prelude to examining the functional roles of Slitrks, we identified eight slitrk orthologs in zebrafish and observed that seven of the eight orthologs were actively transcribed in the nervous system at embryonic, larval, and adult stages. Similar to previous findings in mice and humans, zebrafish slitrks exhibited unique but overlapping spatial and temporal expression patterns in the developing brain, retina, and spinal cord.
Keywords:in situ hybridization  neuronal development  retina  spinal cord  Danio rerio  leucine‐rich repeat (LRR)
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