Efficacy of a Modified Pharmacomechanical Thrombolysis Technique for Endovascular Treatment of Thrombosed Prosthetic Arteriovenous Grafts |
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| Authors: | Sun Young Choi Byung Gil Choi Kum Hyun Han Ho Jong Chun |
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| Affiliation: | 1Department of Radiology and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul 158-710, Korea.;2Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul St. Mary''s Hospital, Seoul 137-040, Korea.;3Department of Internal Medicine, Inje University College of Medicine, Ilsan Paik Hospital, Goyang 411-706, Korea. |
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| Abstract: | ObjectiveWe applied a modified pharmacomechanical thrombolysis (PMT) technique to endovascular treatment of thrombosed arteriovenous (AV) grafts without the use of any mechanical thrombectomy devices. The aim of this study was to evaluate the efficacy of the PMT technique in the treatment of thrombosed AV grafts by analyzing the long-term patency.Materials and MethodsEighty-two patients with thrombosed AV grafts were treated with the PMT technique. AV graft surveillance to detect failing/failed access was followed by endovascular treatment.ResultsThe technical and clinical success rates were 95% and 95%, respectively. The total number of thrombolysis sessions was 279. A post-intervention primary patency rate was 45% and 22% at 12 and 24 months, respectively. The secondary patency rate was 96% and 91% at 12 and 24 months, respectively. No major complications were noticed.ConclusionThe modified PMT technique is effective in endovascular treatment of thrombosed AV grafts. |
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| Keywords: | Hemodialysis access Prosthetic arteriovenous grafts Pharmacomechanical thrombolysis Urokinase Balloon angioplasty |
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