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我市2002年1月~2007年9月小儿药品不良反应分析
引用本文:张瑞杰,董凤琦,李艳红.我市2002年1月~2007年9月小儿药品不良反应分析[J].中国药房,2008,19(26):2061-2062.
作者姓名:张瑞杰  董凤琦  李艳红
作者单位:秦皇岛市妇幼保健院药剂科,秦皇岛市,066000
摘    要:目的:探讨小儿药品不良反应(ADR)的发生因素、一般规律及特征。方法:对我市2002年1月~2007年9月收集到的小儿ADR188例,按照性别、年龄、给药途径、ADR程度、药品类型、ADR累及器官或系统及临床表现等进行分类统计与分析。结果:静脉给药引发ADR95例(占50.5%);引起ADR的药品有112种,抗感染药居首位;ADR累及多器官或系统。结论:临床必须重视小儿ADR的监测和报告,以减少或避免ADR发生。

关 键 词:小儿  药品不良反应  分析

Analysis of Adverse Drug Reactions in Children Appeared Between Jan.2002 and Sept.2007 in Our City
ZHANG Rui-jie,DONG Feng-qi,LI Yan-hong.Analysis of Adverse Drug Reactions in Children Appeared Between Jan.2002 and Sept.2007 in Our City[J].China Pharmacy,2008,19(26):2061-2062.
Authors:ZHANG Rui-jie  DONG Feng-qi  LI Yan-hong
Institution:(Dept. of Pharmacy, Qinhuangdao Maternal and Child Health Hospital, Qinhuangdao 066000, China)
Abstract:OBJECTIVE: To explore the factors, general pattern and characteristics of adverse drug reactions (ADR) in children, METHODS: A total of 188 pediatric ADR reports collected in our city from Jan. 2002 to Sept, 2007 were statistically analyzed in respect of children' s age and sex, route of administration, ADR severity, category of drugs involved, organs or systems involved and clinical manifestations etc. RESULTS: Of the 188 pediatric ADR cases, 95 (50.5%) were induced by intravenous route. A total of 112 kinds of drugs were involved in the ADR, with anti - infective agents showing the highest proportion. Digestive system, neural system, urinary system and skin etc were involved in the ADR. CONCLUSION: Clinic should attach great importance to the monitoring and reporting of pediatric ADR to reduce or avoid the occurrence of ADR.
Keywords:Children  Adverse drug reaction  Analysis
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