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MSCT灌注成像在肾细胞癌诊断中的应用研究
引用本文:孙建男,郭启勇,刘影,高丽媛. MSCT灌注成像在肾细胞癌诊断中的应用研究[J]. 中国临床医学影像杂志, 2007, 18(1): 50-52
作者姓名:孙建男  郭启勇  刘影  高丽媛
作者单位:1. 中国医科大学附属第二医院放射科,辽宁,沈阳,110004
2. 大庆油田总医院CT室,黑龙江,大庆,163001
摘    要:目的:探讨MSCT灌注成像在肾细胞癌检查中的临床应用。方法:接受16排CT肾脏灌注扫描并行手术切除经病理证实的肾细胞癌患者19例,对比剂为优维显(300mgI/ml)50ml,注药速度4ml/s,经Perfusion 3软件处理后进行综合分析。结果:健侧肾脏与患侧肾脏的正常肾组织同一灌注指标无明显差异(P>0.05),肿瘤实质强化,BF值低于正常肾脏皮质,PS值和肿瘤的恶性程度有关,肿瘤坏死区灌注值降低。结论:MSCT灌注成像实现了肾脏血流的定量研究,直观评价肾癌的微循环变化。

关 键 词:肾肿瘤;癌  肾细胞;体层摄影术  螺旋计算机
文章编号:1008-1062(2007)01-0050-03
收稿时间:2006-06-20
修稿时间:2006-10-08

A preliminary study of MSCT perfusion methods in renal cell carcinoma
SUN Jian-nan,GUO Qi-yong,LIU Ying,GAO Li-yuan. A preliminary study of MSCT perfusion methods in renal cell carcinoma[J]. Journal of China Clinic Medical Imaging, 2007, 18(1): 50-52
Authors:SUN Jian-nan  GUO Qi-yong  LIU Ying  GAO Li-yuan
Affiliation:1.Department of Radiology, the Second Affiliated Hospital, China Medical University, Shenyang 110004, China; 2.CT Room, Daqing Oil Field General Hospital, Daqing Heilongjiang 163001, China
Abstract:Objective: To evaluate the application of MSCT perfusion in renal cell carcinoma. Methods: Renal cell carcinoma perfusion was performed in 19 cases with 16 row detector spiral CT, which was confirmed by operation and pathology. Contrast medium(Ultravist 300mg/I) was administered at a dose of 50ml and the rate of injection was 4ml/s. To obtain the perfusion values and maps, data were analyzed by perfusion 3 software. Results: Perfusion value for both sides of the normal kidneys was not obviously different. Compared to normal renal cortex, tumor parenchyma was enhanced obviously and the BF value of tumor was lower. PS value was positively correlated with malignant degree of carcinoma. Perfusion value in the necrotic region of carcinoma decreased significantly. Conclusion: MSCT perfusion image provides quantitative information about renal hemodynamic and could be used to evaluate microcirculation in renal cell carcinoma.
Keywords:kidney neoplasms  carcinoma   renal cell  tomography   spiral computed
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