| 中药粉体流动性表征方法研究 |
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| 引用本文： | 杜焰,赵立杰,冯怡,徐德生,李晓海,王松涛.中药粉体流动性表征方法研究[J].中国中药杂志,2012,37(5):589-593. |
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| 作者姓名： | 杜焰 赵立杰 冯怡 徐德生 李晓海 王松涛 |
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| 作者单位： | 1. 上海中医药大学中药现代制剂技术教育部工程研究中心,上海201203;江西师范大学化学化工学院,江西南昌330022
2. 上海中医药大学中药现代制剂技术教育部工程研究中心,上海,201203 |
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| 基金项目： | 上海市科委项目(09DZ2292000);上海市自然科学基金项目(10ZR1430200);上海市重点学科项目(J50302);江西师范大学科技计划项目(2011) |
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| 摘 要： | 目的:使用合适的方法表征中药粉体的流动性。方法:以流动性较好的直压辅料与中药粉体为原料,对物料粉体使用Carr法和Jenike法测定了流动性。结果:Carr法表征的中药提取物流动性和辅料流动性和Jenike法相差不大,中药提取物流动性明显不如直压辅料。结论:从综合Carr法和Jenike法对各种粉体学表征结果来看,Carr法表征的中药提取物流动性与实际符合较好,Jenike法可以用来指导进料系统的设计。
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| 关 键 词： | 中药粉体 流动性 Carr法 Jenike法 |
| 收稿时间： | 2011/8/10 0:00:00 |
Characterization methods of flowability of traditional Chinese medicine powders |
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| DU Yan,ZHAO Lijie,FENG Yi,XU Desheng,LI Xiaohai and WANG Songtao.Characterization methods of flowability of traditional Chinese medicine powders[J].China Journal of Chinese Materia Medica,2012,37(5):589-593. |
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| Authors: | DU Yan ZHAO Lijie FENG Yi XU Desheng LI Xiaohai and WANG Songtao |
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| Institution: | Engineering Research Center of Modem Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Department of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China;Engineering Research Center of Modem Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Engineering Research Center of Modem Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Engineering Research Center of Modem Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Engineering Research Center of Modem Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Engineering Research Center of Modem Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China |
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| Abstract: | Objective: To characterize the flowability of traditional Chinese medicine (TCM) powders by using appropriate methods. Method: With highly flowable direct compression excipients and Chinese traditional medicine powder as raw materials, the flowability of material powders is determined by the Carr method and the Jenike method. Result: The Carr method and the Jenike method for the determination of the flowability of Chinese herb extract powder and direct-pressing excipients have no obvious difference. But the flowability of Chinese herb extract powder is not as good as direct compression excipients. Conclusion: From the characterization results of both methods, we can find that the Carr method better reflects the actual flowability of TCM extracts, while the Jenike method can be used for guiding the design of the hopper device. |
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| Keywords: | traditional Chinese medicine powders flowability Carr method Jenike method |
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