18F-FDG PET/CT检测淋巴结转移性鳞癌原发灶的价值

目的:探讨 18F-氟脱氧葡萄糖（FDG） PET/CT在淋巴结转移性鳞癌原发灶检测中的临床应用价值。 方法:选取2018年3月至2020年11月于广东省佛山市禅城区中心医院因发现淋巴结转移性鳞癌而原发灶不明行全身 18F-FDG PET/CT检查的56例患者进行回顾性研究，其中男性4...

The value of 18F-FDG PET/CT imaging in detecting the primary foci of lymph node metastatic squamous cell carcinoma

Objective To investigate the clinical value of 18F-FDG PET/CT imaging in detecting primary foci by analyzing images of squamous carcinoma patients with lymph node metastatic. Methods A retrospective analysis was performed on 56 patients (44 males and 12 females, aged 19?81, with a median age of 51), who underwent whole-body 18F-FDG PET/CT for the diagnosis of metastatic squamous carcinoma with unknown primary foci during March 2018 to November 2020 at the Central Hospital of Chancheng District of Foshan City in Guangdong Province. Prior to imaging, the diagnosis of metastatic squamous cell carcinoma was confirmed by pathological examination in all patients, and the primary foci were confirmed by pathological examination or clinical follow-up. To analyze and calculate the detection rate of 18F-FDG PET/CT in the diagnosis of primary lesion and the relationship between primary lesion and lymph node metastasis and maximum standardized uptake value (SUV_max). SUV_max of primary tumor and lymph node metastasis were analyzed by bivariable correlation analysis. Results Among 56 patients, 44 positive cases (42 true positive cases and 2 false positive cases) were detected by 18F-FDG PET/CT, with a detection rate of 75.0% and 1 false negative (nasopharyngeal carcinoma). Primary foci in 11 patients remained unfound by 18F-FDG PET/CT. The SUV_max of primary and metastatic foci were consistent to some extent (r=0.320, P<0.05). Conclusion 18F-FDG PET/CT imaging has good clinical value for the detection of unspecified primary foci in metastatic squamous cell carcinoma, and there is a good correlation between the intensity of glucose metabolism in the primary foci and metastatic foci.