基于文献计量学的耐辐射异常球菌研究态势分析

目的 分析国内外关于耐辐射异常球菌（DR）的研究现状，明确前沿与热点问题，初步评析其发展前景，为进一步的研究提供信息和方向。 方法 以Web of Science和中国知网数据库为文献来源，检索2009至2018年主题词为“耐辐射异常球菌”、“耐辐射奇球菌”、“Deinococcus radiodurans”的相关文献，根据发文量、发文期刊、作者信息、关键词以及国家等进行文献计量分析，同时通过国内外文献可视化分析的权威工具CiteSpace V.5.5软件对以上信息进行多元、分时、动态地分析，探索它们之间的关系，分析其研究的发展态势、热点及前沿领域等。 结果 共纳入1026篇英文文献和157篇中文文献。英文文献数量近十年呈持平递减趋势；中文文献数量则呈波动变化，其引证文献却呈上升的趋势。英文发文量最多的作者是HUA YJ（华跃进）（48篇)，中文发文量最多的作者是陈明（14篇）。国外主要发文期刊是美国的Plos One和Journal of Biological Chemistry，国内的则是《核农学报》；进行这些研究的机构主要是大学和原子能研究中心，发文量前3的国家为美国、中国和法国；研究热点主要围绕DR的抗性基因，具体研究方向较分散。 结论 DR的研究主要集中在其抗性基因，因此其耐辐射的机制今后依然是一个研究热点，且其在医学治疗、农业和环境治理等方面的应用研究具有很大的探索空间。

Trends in Deinococcus radiodurans research based on bibliometrics

Objective To analyze the research status of radiation-resistant abnormal cocci, Deinococcus radiodurans, at home and abroad; identify frontier and hot issues; and preliminarily evaluate future development and prospects in order to provide information and direction for further research. Methods Numerous publications from the Web of Science and China national knowledge infrastructure were examined. Advanced search was used to search for relevant literatures between 2009 and 2018 that contain the keyword "Deinococcus radiodurans". Literature research covered the full spectrum of major indicators, such as the number of literatures published, journals published, author information, keywords, and countries. CiteSpace V.5.5, an authoritative tool for the visual analysis of literatures at home and abroad, was used to analyze the above information. in a multi-dimensional, time-sharing and dynamic way, to explore the relationship among the indicators and analyze the development trends, hotspots, and frontier fields of research. Results A total of 1026 English literatures and 157 Chinese literatures were reviewed. Statistical analyses revealed that the number of English literatures is stable but there is a small fluctuation decline trend in the past 10 years. By contrast, the number of Chinese literatures has fluctuated during the same period. However, the citation of Chinese literatures is increasing year after year. Among Chinese literatures, Hua YJ (Hua Yuejin) ranked first with 48 English papers, and Chen Ming has published the most in Chinese literatures with 14 papers. The main international journals are Plos One and Journal of Biological Chemistry, and the most popular domestic journal is the Journal of Nuclear Agricultural Sciences. The main research institutions are universities and atomic research centers, and the top three countries are America, China and France. Their studies focused on the resistance genes of Deinococcus radiodurans, but their specific research directions are scattered. Conclusions Current research on Deinococcus radiodurans is focused on its resistance genes. Therefore, the mechanism of its radiation resistance will still be a research hotspot in the future, and its application in medical treatment, agriculture, and environmental governance has a lot of room for exploration.