体外受精-胚胎移植术后双胎脐带帆状附着致双胎生长受限一例

脐带帆状附着是指脐带附着于胎盘边缘的胎膜上,多见于初产妇、多胎妊娠和采用辅助生殖技术助孕的孕妇。由于其特殊的解剖关系,脐带帆状附着可以发生母儿不良妊娠结局,轻者表现为胎儿生长缓慢,严重者可导致胎死宫内。在治疗方面,尚无特定有效的药物干预,临床处理主要取决于胎儿孕周及其宫内状况。现回顾1例体外受精-胚胎移植术后双胎均为脐带帆状附着并导致双胎生长受限的病例,以期拓宽妇产科医生的学术视野并提高对该病的警觉。

A Case Report on Twin Fetuses Growth Restriction Caused by Both of Velamentous Cord Insertion after In Vitro Fertilization-Embryo Transfer

Velamentous cord insertion(VCI) refers to the attachment of umbilical cord to the fetal membrane at the edge of placenta, which is more common in primiparas, multiple pregnancies and pregnant women who used human assisted reproductive technology. Because of its special anatomic position, VCI can lead to adverse pregnancy outcomes of both mother and infant. Mild cases show fetal growth retardation, and severe cases show intrauterine fetal death. In terms of treatment, there is no specific and effective drug intervention, and the clinical treatment mainly depends on the gestational age and intrauterine condition of the fetus. We reported a clinical case of twin fetuses growth restriction caused by both of VCI after in vitro fertilization-embryo transfer. We hope to improve the academic vision and the understanding of this disease in obstetricians and gynecologists.