| 微小RNA在神经发生中的调控作用 |
| |
| 引用本文： | 潘长福,汪泱,邓志锋.微小RNA在神经发生中的调控作用[J].国际脑血管病杂志,2010,18(6). |
| |
| 作者姓名： | 潘长福 汪泱 邓志锋 |
| |
| 作者单位： | 1. 南昌大学第二附属医院神经外科,330006
2. 南昌大学泌尿外科研究所,330006 |
| |
| 基金项目： | 国家科技支撑计划，国家自然科学基金资助项目 |
| |
| 摘 要： | 神经发生是指神经干细胞自我增殖和分化成为新的神经元,并整合入神经网络的生物学过程,包括胚胎时期神经发牛和成体时期的神经发生.研究表明,微小RNA在神经发生中发挥着重要的调控作用.文章就近年来微小RNA在胚胎和成体神经发生调控中的分子机制以及脑缺血后神经发生过程中微小RNA的可能调控作用进行了综述.
|
| 关 键 词： | 微小 RNA 神经发生 干细胞 脑缺血 细胞分化 |
The regulatory roles of microRNAs in neurogenesis |
| |
| PAN Chang-fu,WANG Yang,DENG Zhi-feng.The regulatory roles of microRNAs in neurogenesis[J].International Journal of Cerebrovascular Diseases,2010,18(6). |
| |
| Authors: | PAN Chang-fu WANG Yang DENG Zhi-feng |
| |
| Abstract: | Neurogenesis refers to a biological process of neural stem cells self-proliferate and differentiate into new neurons, and are integrated into the neural networks, including the embryonic neurogenesis and adult neurogenesis. Studies have suggested that microRNAs (miRNAs) play vital regulatory roles in neurogenesis. This article reviews the molecular mechanisms of miRNAs in the regulation of embryonic and adult neurogenesis as well as the possible regulatory roles of miRNAs in the process of neurogenesis after cerebral ischemia. |
| |
| Keywords: | MicroRNAs Neurogenesis Stem cells Brain ischemia Cell differentiation |
| 本文献已被 万方数据 等数据库收录！ |
|
