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鲎试剂检查醒脑静注射液细菌内毒素的探讨
引用本文:叶树林,王晓蕾.鲎试剂检查醒脑静注射液细菌内毒素的探讨[J].军医进修学院学报,2011,32(5):469-470.
作者姓名:叶树林  王晓蕾
作者单位:1. 解放军总医院院务部,北京,100853
2. 解放军总医院药品保障中心,北京,100853
摘    要:目的探讨用鲎试剂检查醒脑静注射液细菌内毒素方法。方法根据《中国药典》2005年版Ⅱ部收载的细菌内毒素检查法的要求进行实验。结果醒脑静注射液经10倍稀释时不干扰鲎试剂与细菌内毒素的凝胶反应。结论细菌内毒素检查法适用于检测醒脑静注射液的内毒素。

关 键 词:醒脑静注射液  干扰试验  鲎试剂  细菌内毒素检查

Detection of bacterial endotoxin in Xingnaojing injection with Tachypleus Amebocyte lysate
YE Shu-lin,WANG Xiao-lei.Detection of bacterial endotoxin in Xingnaojing injection with Tachypleus Amebocyte lysate[J].Academic Journal of Pla Postgraduate Medical School,2011,32(5):469-470.
Authors:YE Shu-lin  WANG Xiao-lei
Institution:YE Shu-lin1,WANG Xiao-lei2 1Department of Logistic service,2Department of Pharmacy Chinese PLA General Hospital,Beijing 100853,China
Abstract:Objective To study the method for the detection of bacterial endotoxin in Xingnaojing injection with Tachypleus Amebocyte lysate(TAL).Methods Experiments were performed according to the bacterial endotoxin tests covered in Chinese Pharmacopeia 2005(part 2).Results Xingnaojing injection did not interfere with its gel reaction to the bacterial endotoxin when it was diluted 10-fold.Conclusion Bacterial endotoxin test can be used to detect bacterial endotoxin in Xingnaojing injection.
Keywords:Xingnaojing Injection  Interference Test  Tachypleus Amebocyte Lysate  Bacterial Endotoxin Test  
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