Type III Secretion-Dependent Hemolytic Activity of Enteropathogenic Escherichia coli |
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| Authors: | Jonathan Warawa B. Brett Finlay Brendan Kenny |
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| Affiliation: | Department of Pathology and Microbiology, School of Medical Sciences, Bristol, England. |
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| Abstract: | Enteropathogenic Escherichia coli (EPEC) was found to exhibit a type III secretion-dependent, contact-mediated, hemolytic activity requiring the EspA, EspB, and EspD secreted proteins. EspB and EspD display homology to pore-forming molecules. Our data suggest a mechanism to explain the requirement for all three Esp proteins in the transfer of EPEC proteins, such as Tir, into target cells. |
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