市炎支原体肺炎合并支气管哮喘患儿的血小板活化状态研究

目的研究观察肺炎支原体肺炎合并支气管哮喘患儿的血小板活化状态。方法选取2011年6月-2013年6月于该院进行诊治的56例肺炎支原体肺炎合并支气管哮喘患儿为观察组，同时将同期的56名体检示健康儿童设为对照组，然后将两组儿童的血小板活化指标进行检测与比较，并比较观察组中轻度、中度、重度哮喘与急性、慢性感染患儿的检测结果。结果观察组患儿的血小板活化指标均高于对照组，且观察组中重度哮喘患儿高于轻度与中度哮喘患儿。中度哮喘患儿则高于轻度哮喘息儿，差异有统计学意义（P〈0．05），而急性与慢性感染患儿之间差异无统计学意义（P〉0．05）。结论肺炎支原体肺炎合并支气管哮喘患儿的血小板活化指标呈现较高的状态。因此应注重对患儿此方面的监测与改善。

Study on the Platelet Activation State of Children with Mycoplasma Pneu- moniae Pneumonia and Bronchial Asthma

Objective To study and observe the platelet activation state of children with mycoplasma pneumoniae pneumonia and bronchial asthma. Methods 56 children with mycoplasma pneumoniae pneumonia and bronchial asthma diagnosed and treated in our hospital from June, 2011 to June, 2013 were selected as the observation group, 56 healthy children underwent health examina- tion during the same period were the control group. Then the platelet activation indexes of two groups were detected and compared. And the detection results of the children with mild asthma, moderate asthma, severe asthma and acute, chronic infection in the ob- servation group were compared, too. Results The platelet activation indexes of the observation group were all higher than those of the control group. In the observation group, the detection results of the children with severe asthma were all higher than those of the children with mild asthma or moderate asthma, and the detection results of the children with moderate asthma were higher than those of the children with mild asthma （P〈0.05）, the differences were statistically significant, but the difference in detection results between the children with acute infection and the children with chronic infection was not statistically significant（P〉0.05）. Conclu- sion The platelet activation indexes of children with mycoplasma pneumoniae pneumonia and bronchial asthma all show higher state, so its monitoring and improvement of children should be paid attention.