| 锰对雄性大鼠睾丸毒性的病理学研究 |
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| 引用本文： | 纪淑琴,葛利辉,姜岳明,陆继培,徐胜美,胡万达.锰对雄性大鼠睾丸毒性的病理学研究[J].中国男科学杂志,1995(1). |
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| 作者姓名： | 纪淑琴 葛利辉 姜岳明 陆继培 徐胜美 胡万达 |
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| 作者单位： | 广西医科大学劳动卫生职业病教研室，广西南宁市卫生防疫站，广西医科大学病理解剖学教研室 |
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| 摘 要： | 每天给大鼠腹腔注射氯化锰１５ｍｇ／ｋｇ，连续６０天及８４天。结果染锰大鼠睾丸重量下降（Ｐ＜０．０１），睾丸脏器系数也明显降低（Ｐ＜０．０１）；血清锰虽无明显增高，但睾丸组织中的锰含量却增高；光镜检查：睾丸曲细精管呈不同程度的变性，管内生精细胞数目减少、缺如，精子形成少或无。
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| 关 键 词： | 锰，睾丸，生殖毒理 |
STUDY OF MANGAN ESE TOXICITY IN TESTICU LAR PATHOLOGICAL CHANGES IN MALE RAT |
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| Shu-Qin,et al.STUDY OF MANGAN ESE TOXICITY IN TESTICU LAR PATHOLOGICAL CHANGES IN MALE RAT[J].Chinese Journal of Andrology,1995(1). |
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| Authors: | Shu-Qin |
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| Abstract: | mg/(kg.d)manganese and normal saline were injected intraperitoneally separately to rats for sixty days and eighty-four days.The results showed that the testis weight and organic coefficient were decreased significantly(p<0.01).The content of manganese in serum was not increased.But the content of manganese in testis tissues was increased significantly.The convoluted seminiferous tubules showed degeneration in various degree.The number of spermatid was markedly depleted and no spematocytes were seen in the tubules. |
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| Keywords: | Manganese Testis Reproductive toxicity |
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