The effect of demineralized bone matrix gel on bone ingrowth and fixation of porous implants |
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Authors: | Cook Stephen D Salkeld Samantha L Patron Laura P Barrack Robert L |
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Affiliation: | Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA. scook2@tulane.edu |
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Abstract: | The presence of demineralized bone matrix (DBM) gel did not enhance or accelerate attachment strength or bone ingrowth and resulted in a significant decrease in implant interface attachment strength at 3 weeks. Hydroxyapatite (HA) coating resulted in significant increases in interface shear strength and bone ingrowth compared with non-HA-coated porous implants at all time periods. The HA-coated implants achieved greater attachment strength and bone ingrowth at earlier time periods and maintained greater attachment strength at long-term periods. The results of this study indicate that in the presence of a good bone-implant interference fit, there is no beneficial effect in applying DBM gel to a porous-coated or HA-coated porous implant surface. The small amount that can be applied and the degree of osteoinductivity of DBM seem to preclude it from having a significant biologic effect. |
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