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Bayesian population analysis of a washin–washout physiologically based pharmacokinetic model for acetone |
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| Authors: | Anna-Karin M rk, Fredrik Jonsson,Gunnar Johanson |
| Affiliation: | aWork Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden;bPharsight, a Certara company, St. Louis, MO, USA |
| Abstract: | |
| Keywords: | PBPK Bayesian analysis Hierarchical model Human Markov chain Monte Carlo simulation Respiratory washin– washout Sensitivity analysis |
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