| 丙型肝炎病毒核心蛋白生物学功能研究进展 |
| |
| 引用本文： | 李建蓉,公瑞煜. 丙型肝炎病毒核心蛋白生物学功能研究进展[J]. 大理医学院学报, 2001, 10(1): 57-59 |
| |
| 作者姓名： | 李建蓉 公瑞煜 |
| |
| 作者单位： | [1]大理医学院微生物与免疫学教研室，云南大理671000 [2]同济医科大学药学院，武汉430030 |
| |
| 摘 要： | 目的：概述丙型肝炎病毒核心蛋白的主要生物学功能。方法：查阅并参考国外近年20多篇相关献资料。结果：综述了丙型肝炎病毒核心蛋白T、B细胞表位及对细胞周期的影响。结论：核心蛋白是丙型肝炎病毒疫苗研究的靶区域，与病毒持续性感染、肝细胞肝癌的发生密切相关，对其深入研究有助于探讨丙型肝炎病毒的致病机制及其防治。
|
| 关 键 词： | 丙型肝炎病毒 核心抗原 表位 细胞周期 肝癌 |
| 文章编号： | 1004-4442(2001)-01-0057-03 |
| 修稿时间： | 2000-02-28 |
Research Advances of Biology Function of Hepatitis C Virus Core Protein |
| |
| LI Jian-rong, GONG Rui-yu. Research Advances of Biology Function of Hepatitis C Virus Core Protein[J]. Journal of Dali Medical College, 2001, 10(1): 57-59 |
| |
| Authors: | LI Jian-rong GONG Rui-yu |
| |
| Affiliation: | LI Jian-rong1, GONG Rui-yu2 |
| |
| Abstract: | Objective:To generalize the biological function of hepatitis C Virus(HCV)core protein.Method:More than 20 current foreign literatures were read and reviewed.Results:There are some T and B cell epitopes on HCV core protein,and HCV core protein can affect cell cycle.Conclusions:HCV core protein was the target region of studying vaccine,related with persistent infection and hepatocarcinoma.The reviewed results are beneficial to study the HCV pathogenesis and therapy for hepatitis C. |
| |
| Keywords: | Heaptitis C virus Core antigen Epitopes Cell Cycle Hepatocarcinoma |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
