Abstract: | A modification of the highly sensitive method of electrophoresis-precipitation in polyacrylamide gel for the detection of virus hepatitis B antigen (HBsAg) and antibodies against it is described. The method completely preserves the specificity of immunodiffusion in gel, but is 1000–2000 times more sensitive for the detection of HBsAg. The method has given good results with the sera of patients with various diseases. It detects HBsAg more efficiently than other methods used previously.Scientific Experimental-Production Group, Laboratory of Cellular Immunity, N. F. Gamaleya Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR O. V. Baroyan.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 4, pp. 508–509, April, 1977. |