改良Sugiura手术加自体脾移植治疗门静脉高压症的临床研究

目的：评价改良Sugiura手术加自体脾移植治疗门静脉高压症的效果。方法：应用改良Sugiura手术力暗体脾移植治疗门静脉高压症患者45例（研究组）．与同时期45例行贲门周围血管离断术的患者（对照组）进行对比研究。结果：研究组术后无死亡病例，近期止血效果确切，随访时间0.5～4年，肝性脑病发生率为4．4％（2／45），再出血率为2．2％（1，45）；术后所有患者食管下段静脉曲张消失或明显好转；术后再出血率及静脉消失率两组比较差异均有统计学意义（P〈o．05）o研究组术后2个月血清Tuftsin和IgM水平下降不显著，术后随访移植睥块同位素显像呈阳性，而对照组无阳性显像。结论：改良Sugiura手术加部分自体脾移植手术操作较简单、再出血率低、并发症少且保留脾脏的免疫功能，是一种值得摊广的治疗门静脉高压痱手术方法。

Clinical study of modified sugiura procedure plus spleen autotransplatation in the treatment of portal hypertension

Objective: To evaluate the effect of modified Sugiura procedure plus spleen autotrans- plantation in treatment of portal hypertension. Methods: From 2003 to 2007,45 patients with portal hy- pertension underwent modified Sugiura procedure plus spleen autotransplantation, and 45 patinets under- went pericardial devascularization . Results: There was no postoperational mortality. The immediate effect on the hemorrhage and recent response of the patients were satisfactory. After 0.5 years to 4 years of follow u...