原发性结直肠恶性淋巴瘤20例临床分析

目的掌握原发性结直肠恶性淋巴瘤的诊断和治疗。方法回顾性分析２０例原发性结直肠恶性淋巴瘤的临床病理特点。结果病变主要发生在右半结肠，以腹块（８５％）、腹痛（７５％）、体重下降（４５％）以及血便（４０％）、腹胀（３０％）等为主要特点。１例为霍奇金淋巴瘤；１９例为非霍奇金淋巴瘤，其中１８例为弥散型Ｂ细胞型。治疗宜采用手术、化疗、放疗等的综合治疗方法。结论临床、影像学和内窥镜检查结合可提高诊断率；根治切除者预后较好；规范性化疗可以提高远期疗效。

PRIMARY MALIGNANT COLORECTAL LYMPHOMA A REPORT OF 20 CASES

PURPOSE To review the diagnostic and therapeutic experience on malignant lymphoma of colorectum.METHODS A retrospective study of 20 cases.RESULTS This disease originates mainly in the right semicolon. The clinical manifestations were characterized by abdominal mass (85% ),abdominal pain (75 % ),weight loss (45 % ),bloody stool (40%),abdominal distension (30% )etc. The main pathological type was non-Hodgkin's lymphoma (18 cases). The methods of treatment included surgery, chemotherapy and radiotherapy. The mean survival time after treatment was 26 months, 6 patients were alive and well when seen at last follow-up. The prognosis should be better after radical resection. In order to improve long-term results,it is essential to give full courses of chemotherapy.CONCLUSIONS Combination of clinical methods, imaging techniques and fibroscopy examinations can improve the diagnosis.