肝细胞癌微血管形态与其临床病理学特性关系的研究

目的 探讨肝细胞癌肿瘤微血管形态特征与其临床病理学特性的关系.方法 收集我院手术切除前未做过栓塞治疗的肝细胞癌标本55例,对此组肝细胞癌病理标本做了肿瘤微血管形态分型、分化级别划分、肿瘤大小测量、有无包膜及卫星结节鉴定,并对各观察指标做相关统计分析.结果 肝癌细胞分化级别、大小与肿瘤微血管分型级别呈正相关趋势.无包膜的肝癌微血管分型级别高于有包膜的肝癌.肝癌微血管分型在肿瘤有无卫星结节间无差别.结论 肝癌在生长的不同阶段,其肿瘤微血管形态特征不同,并有一定的规律.低分化、大肝挝癌、无包膜者微血管分型级别较高.

The Study of the Relationship between Morphological Characteristics of Tumor Microvessels and the Clinical Pathology Features of the Hepatocellular Carcinoma

Objective To study the relationship between the morphological characteristics of tumor microvessel and the clinical pathology features of HCC.Methods To collect 55 primary hepatocellular carcinoma tissues preoperatively without artery embolotherapy,and survey the microvessels typing,differentiation level,tumors diameter,envelope and satellitic nodus.The outcomes were statistically counted.Results Tumor microvessels typing degrees has the tendency of positive correlation with differentiation level and tumors diameter.Tumor microvessel typing degrees in HCC without envelope is higher than in HCC with envelope.Tumor microvessel typing is no difference between HCC without satellitic nubble and HCC with satellitic nubble.Conclusion HCC's morphological characteristics of tumor microvessels were distinctive in different growing phases,and had definite rule.Tumor microvessels typing degree is higher in low-grade differentiation level HCC,large HCC and HCC without envelope.