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| 应力性骨折动物模型建立方法的研究及评价 | |
| 引用本文： | 宋天一,罗二平,申广浩,张星,甘文科,陈耀明. 应力性骨折动物模型建立方法的研究及评价[J]. 医疗卫生装备, 2009, 30(2): 21-22 |
| 作者姓名： | 宋天一 罗二平 申广浩 张星 甘文科 陈耀明 |
| 作者单位： | 1. 第四军医大学,生物医学工程系,西安,710032;济南军区总医院,济南,250031 2. 第四军医大学,生物医学工程系,西安,710032 3. 第四军医大学,军事预防医学系,西安,710032 |
| 基金项目： | 军队重大医药卫生扩试项目 |
| 摘 要： | 目的：研制一种动物疲劳性训练实验系统，以期快速建立应力性骨折动物模型。方法：采用MSP430F4270单片机控制高压发生器输出频率和时长可调的高压脉冲，迫使实验兔进行跳跃运动；训练周期结束后，采用骨闪烁显像术对建模方法进行评价。结果：应用该系统成功地建立了兔应力性骨折模型。结论：该系统能方便地调节实验动物的训练强度和训练量，工作稳定，可靠性高，具有建模时间短、成功率高等优点。 |
| 关 键 词： | 动物模型 应力性骨折 MSP430 骨闪烁显像 |
Study and Evaluation on Establishment Method of Stress Fracture Animal Model |
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| SONG Tian-yi,LUO Er-ping,SHEN Guang-hao,ZHANG Xing,GAN Wen-ke,CHEN Yao-ming. Study and Evaluation on Establishment Method of Stress Fracture Animal Model[J]. Chinese Medical Equipment Journal, 2009, 30(2): 21-22 | |
| Authors: | SONG Tian-yi LUO Er-ping SHEN Guang-hao ZHANG Xing GAN Wen-ke CHEN Yao-ming |
| Affiliation: | SONG Tian-yi, LUO Er-ping, SHEN Guang-hao, ZHANG Xing, GAN Wen-ke, CHEN Yao-ming (1.Facuhy of Biomedical Engineering, the 4th Military Medical University, Xi＇an 710032, China; 2.Facuhy of Military Preventive Medicine, the 4th Military Medical University, Xi＇an 710032, China; 3.General Hospital of Jinan Military Area Command, Jinan 250031, China) |
| Abstract: | Objective To design an exercise experimental system for the rapid establishment of stress fracture animal model. Methods The system utilized MCU controlled high voltage generator to export high voltage impulse, which can oblige rabbits to run and jump. After training, skeletal scintigraphy was used to evaluate the method. Results A rabbit stress fracture model was established based on the system. Conclusion The system can adjust training intensity and quantity expediently with high reliability, thus animal mode is established successfully in short time. |
| Keywords: | MSP430 |
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