| 中药合子草的药理及毒理作用研究 |
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| 引用本文： | 倪萍,王立新,吴启南. 中药合子草的药理及毒理作用研究[J]. 现代中药研究与实践, 2001, 15(4): 14-15 |
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| 作者姓名： | 倪萍 王立新 吴启南 |
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| 作者单位： | 1. 江苏省盐城市药品检验所
2. 南京中医药大学 |
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| 摘 要： | 目的 :研究合子草水煎液、总皂苷对小鼠免疫功能的影响及急性毒性试验。方法 :通过实验观察合子草对小鼠免疫功能的影响 ,用 Bliss法测定半数致死量进行急性毒性试验。结果 :可明显增强小鼠的免疫功能 ,水煎液 L D5 0 为 132 .34g/ kg,总皂苷 L D5 0 为 7.17g/ kg。结论 :合子草可明显增强小鼠的免疫功能其活性成分与毒性成分为总皂苷
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| 关 键 词： | 合子草 总皂苷 药理作用 毒性试验 |
| 修稿时间： | 2001-03-23 |
Pharmacological and Toxicological Research on Hezicao |
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| Ni Ping. Pharmacological and Toxicological Research on Hezicao[J]. Research and Practice on Chinese Medicines, 2001, 15(4): 14-15 |
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| Authors: | Ni Ping |
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| Abstract: | OBJECTIVE: To study the effects and acute toxicity of water extraction of Hezicao and its total saponin on immunity function.METHODS:Utilized experiments to survey the effects of immunity function of rats. The Bliss method was used determine LD 50 in experiments of acute toxicity.RESULTS:Hezicao can enhance the weight of thymus and spleen of mice. LD 50 of water extraction is 132.34g·kg -1 , the LD 50 of total saponin is 7.17g·kg -1 .CONCLUSIONS:Hezicao had significant effects on improving the immunity function. The activated poisonous position is perhaps total saponin in Hezicao. |
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| Keywords: | Hezicao total saponin pharmacological effects acute toxicity |
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