| 幽门螺杆菌感染与特发性血小板减少性紫癜的相关性研究 |
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| 引用本文： | 陶丽菊.幽门螺杆菌感染与特发性血小板减少性紫癜的相关性研究[J].医学综述,2009,15(17):2605-2608. |
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| 作者姓名： | 陶丽菊 |
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| 作者单位： | 右江民族医学院附属医院血液科,广西,百色,533000 |
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| 基金项目： | 广西百色市科技局立项课题 |
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| 摘 要： | 特发性血小板减少性紫癜(ITP)是一种自身免疫出血性疾病,其病因迄今尚未完全清楚,研究认为幽门螺杆菌(HP)感染可能是部分ITP患者发病的原因,HP导致ITP的发病机制可能与幽门螺杆菌细胞毒素相关基因A蛋白与血小板抗原间产生交叉反应、HP诱发机体免疫失调、HP感染后宿主遗传的易感性以及HP Lew is抗原和HP尿素酶B的作用有关。
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| 关 键 词： | 特发性血小板减少性紫癜 幽门螺杆菌 病因 发病机制 |
The Relativity between Helicobacter Pylori and Idiopathic Thrombocytopenic Purpura |
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| TAO Li-ju.The Relativity between Helicobacter Pylori and Idiopathic Thrombocytopenic Purpura[J].Medical Recapitulate,2009,15(17):2605-2608. |
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| Authors: | TAO Li-ju |
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| Institution: | TAO Li-ju. (Department of Hematology, the Affiliated Hospital of Youjiang Medical College for Nationalities, Baise 533000, China) |
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| Abstract: | Idiopathic thrombocytopenic purpura（ITP） is an autoimmune hemorrhagic disease, but its pathogeny is not very clear up to now. The studies considered that HP infection may be the pathogeny for part of patients with ITP, and the pathogenesis of it may be relative with crossing reaction between protein of HP cytotoxin associatied gene A and platele antigen, immune disorder induced by HP, susceptibility inherit from host after HP infection and the function of HP Lewis antigen and HP urase B. |
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| Keywords: | Idiopathic thrombocytopenic purpura Helieobacterpylori Pathogeny Pathogenesis |
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