国产封堵器闭合房间隔缺损过程中的短暂ST段抬高2例（英文）

目的国产房间隔封堵器闭合房间隔缺损的安全性和有效性已得到证实。我们报告在使用国产封堵器闭合房间隔缺损过程中出现的短暂ST段抬高现象2例。方法适合进行经皮封堵术的房间隔缺损患者35例,使用北京华医圣杰公司生产的房间隔封堵器进行封堵。术前经胸超声充分评估缺损的大小、位置、与周围结构的距离以及房间隔的软硬边缘等,选择封堵器要与缺损的伸展直径相匹配。手术过程在局部麻醉或者基础麻醉下进行,术中使用经胸超声引导。封堵器释放后有效闭合缺损、位置稳定且不影响周边结构视为手术成功。术后3,6,12月进行随访。结果在35例患者中有2例在封堵器释放过程中,出现短暂性ST段抬高超过2mV,伴有心绞痛发作。心电图改变和症状发作平均持续时间（4.2±2.2）min,2例心电图改变均发生于II,III和aVF导联,此过程伴有心率减慢和血压降低。静脉注射硝酸甘油后心电图和症状没有得到即刻改善,但封堵器沿鞘管被收回后心电图立即改善、症状逐渐消失。换用较小型号的封堵器闭合房间隔缺损后,没有引起任何血流动力学异常和短暂性心电图改变。随访3,6,12月没有发现心肌缺血和心绞痛发作。结论经导管闭合房间隔缺损过程中出现的短暂ST段抬高现象,可能与所选封堵器直径过大,刺激房间隔有关。

Transient ST-segment-elevation during transcatheter closure of atrial septal defect(ASD) with ASD occluder made in China:A report of two cases

AIM The safety and efficacy of atrial septal defect(ASD) occluder(ASDO) made in China for transcatheter closure of ASD have investigated prospectively. We report the phenomenon of transient ST-segment-elevation(TSTE) during transcatheter closure of ASD with ASDO made in China in this single-centre study. METHODS A total of 35 consecutive patients in whom a septal defect occluder (Huayishengjie Inc.,Beijing,China) was used to close a clinically significant ASD were included in our study.All procedures perfor...