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Immunoglobulin G(κ) [IgG(κ)] and IgG(λ) Paraproteinemia in a Child with AIDS and Response to Highly Active Antiretroviral Therapy |
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| Authors: | Filiz Odabasi Seeborg Hannah Gay Lorenz M. Schmiege III David Bernard William T. Shearer |
| Affiliation: | Section of Allergy & Immunology, Texas Children''s Hospital and Baylor College of Medicine,1 Department of Pathology, Baylor College of Medicine, Houston, Texas 77030,3 Pediatric Infectious Disease Division, University of Mississippi Medical Center, Jackson, Mississippi 39213,2 Department of Pathology, The Methodist Hospital, Houston, Texas 77030, and Weill Medical College of Cornell University, New York, New York 100214 |
| Abstract: | We report an 8-year-old boy with AIDS, extremely elevated serum immunoglobulin G (IgG) concentration and IgG kappa [IgG(κ)] and IgG lambda [IgG(λ)] paraproteinemia. This paraproteinemia partially responded to highly active antiretroviral therapy. This case emphasizes the importance of controlling B-cell activation. |
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