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Stem cells: an autonomous cell producing system |
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| Authors: | Emanuel Neĉas |
| Affiliation: | Department of Pathophysiology, Faculty of General Medecine, Charles University, Prague, Czechoslovakia |
| Abstract: | Stem cells have been traditionally considered to be a reserve population, in which the primary control is the rate of differentiation. Alterations in proliferation rate are then considered to be the results of changes in the number of stem cells. This article suggests that perhaps the reverse is true, namely that the rate of stem cell production is primarily controlled, and not the number of stem cells. |
| Keywords: | Stem cells haematopoiesis proliferation control CFU-s colony forming unit—spleen burst forming unit—erythroid CFC-GM colony forming cell—granuloid, macrophage |
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