Antihistone antibodies in linear scleroderma variants |
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| Authors: | el-Azhary Rokea A Aponte Carole C Nelson Audrey M Weaver Amy L Homburger Henry A |
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| Affiliation: | Department of Dermatology, Mayo Clinic, Rochester, MN 55905, USA. elazhary.rokea2@mayo.edu |
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| Abstract: | BACKGROUND: Linear scleroderma occurs as two clinically distinct variants: the frontoparietal en coup de sabre type, and the torso-extremity type. Antihistone antibodies (AHAs), which traditionally are markers for drug-induced lupus, may also be linked to linear scleroderma. METHODS: Retrospective review of all patients presenting with linear scleroderma who had AHA titers measured. RESULTS: A total of 35 patients were identified. Twenty patients with linear scleroderma of the torso and/or extremities comprised 14 pediatric patients (
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