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Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
Affiliation:1. Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA;2. Divisions of Radiation Cancer Research, Research Center for Radio-Senescence, Korea Institute of Radiological and Medical Sciences, Seoul, Korea;3. Department of Biomedical Convergence Science and Technology, Kyungpook National University, Daegu, Korea;4. Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea;5. Icahn School of Medicine at Mount Sinai, New York, NY, USA;6. Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA;7. Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA;8. Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA;9. Department of Neurology, Weill Cornell Medicine, New York, NY, USA;10. Department of Medicine, MetroHealth Campus, School of Medicine, Case Western Reserve University, Cleveland, OH, USA;11. Department of Neurology, UVA Cancer Center, University of Virginia Health System, Charlottesville, VA, USA;12. Institute for Refractory Cancer Research, Samsung Medical Center, Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Department of Neurosurgery Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Abstract:
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  • Keywords:glioblastoma  tissue factor  senescence  therapeutic resistance  tumor microenvironment
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