首页 | 本学科首页   官方微博 | 高级检索  
检索        


The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients
Institution:1. Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany;2. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA;3. Arnie Charbonneau Cancer Research Institute, University of Calgary, Calgary, Canada;4. Tom Baker Cancer Center, Department of Hematology and Oncology, Calgary, Canada;5. Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany;6. Department of Neurology, MCTN, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany;7. Division of Chromatin Networks, BioQuant Center & German Cancer Research Center (DKFZ), Heidelberg, Germany;8. Faculty of Biosciences, Heidelberg University, Heidelberg, Germany;9. Department of Neuropathology, Freiburg University Hospital, Freiburg, Germany;10. Helmholtz Institute of Translational Oncology (HI-TRON), Mainz, Germany;11. National Center for Tumor Diseases (NCT), Heidelberg, Germany;12. DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim Germany;13. Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany
Abstract:
><ol class=
  • Download : Download high-res image (156KB)
  • Download : Download full-size image
  • Keywords:T cell exhaustion  multiple myeloma  single-cell RNA-seq  TCR repertoire  tumor microenvironment  immunotherapy  bispecific antibodies  T cell engager  tumor immunology  BCMA
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号