RAS Signaling Gone Awry in the Skin: The Complex Role of RAS in Cutaneous Neurofibroma Pathogenesis,Emerging Biological Insights |
| |
| Affiliation: | 1. Division of Hematology-Oncology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA;2. Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA;3. Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA;4. Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, USA;5. Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA;6. Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA;7. School of Cancer Sciences, University of Glasgow, Glasgow, Scotland;8. Children’s Tumor Foundation, New York, New York, USA;9. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;10. Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA;11. Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan, USA;12. Helen DeVos Children’s Hospital, Spectrum Health System, Grand Rapids, Michigan, USA;13. College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA;14. Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA |
| |
| Abstract: | |
| |
| Keywords: | Akt" },{" #name" :" keyword" ," $" :{" id" :" kwrd0015" }," $$" :[{" #name" :" text" ," _" :" protein kinase B cNF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0025" }," $$" :[{" #name" :" text" ," _" :" cutaneous neurofibroma ERK" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" extracellular signal−related kinase FDA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" Food and Drug Administration GAP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" GTPase-activating protein GDP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" guanosine diphosphate GEMM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" genetically engineered mouse model GRD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" GTPase-activating protein−related domain LOH" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" loss of heterozygosity MEK" },{" #name" :" keyword" ," $" :{" id" :" kwrd0105" }," $$" :[{" #name" :" text" ," _" :" MAPK/extracellular signal−regulated kinase syndical MEKi" },{" #name" :" keyword" ," $" :{" id" :" kwrd0115" }," $$" :[{" #name" :" text" ," _" :" MAPK/extracellular signal−regulated kinase syndical inhibitor NFAF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0125" }," $$" :[{" #name" :" text" ," _" :" neurofibroma-associated fibroblast NF1" },{" #name" :" keyword" ," $" :{" id" :" kwrd0135" }," $$" :[{" #name" :" text" ," _" :" neurofibromatosis type 1 PI3K" },{" #name" :" keyword" ," $" :{" id" :" kwrd0145" }," $$" :[{" #name" :" text" ," _" :" phosphoinositide 3-kinase pNF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0155" }," $$" :[{" #name" :" text" ," _" :" plexiform neurofibroma SCF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0165" }," $$" :[{" #name" :" text" ," _" :" stem cell factor SCP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0175" }," $$" :[{" #name" :" text" ," _" :" Schwann cell precursor |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
