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forflox-6化疗方案对晚期直肠癌术后辅助化疗的帮助及预后分析
引用本文:郑周红,朱婷娜,徐刚潮,张晓威. forflox-6化疗方案对晚期直肠癌术后辅助化疗的帮助及预后分析[J]. 罕少疾病杂志, 2020, 27(3): 64-65,77. DOI: 10.3969/j.issn.1009-3257.2020.03.023
作者姓名:郑周红  朱婷娜  徐刚潮  张晓威
作者单位:广东省惠东县人民医院外一科 广东惠州 516300;广东省惠东县人民医院外一科 广东惠州 516300;广东省惠东县人民医院外一科 广东惠州 516300;广东省惠东县人民医院外一科 广东惠州 516300
摘    要:目的探讨对晚期直肠癌,在术后行辅助化疗中采用forflox-6化疗方案的治疗效果及预后情况。方法随机选取60例晚期直肠癌患者为研究对象,将研究对象分成两组,即研究组与对照组每组各30例,两组均采取手术治疗,在术后予以对照组使用xelox辅助化疗治疗,予以研究组使用forflox-6辅助化疗治疗,观察两组治疗效果及治疗期间毒副反应情况。结果研究组治疗总有效率为90.00%,明显高于对照组63.33%的总有效率(P<0.05);研究组化疗期间在骨髓抑制、肝功能损伤、恶心呕吐、腹泻各种毒副反应的总发生率上明显低于对照组,差异有统计学意义(P<0.05)。结论对晚期直肠癌,在行手术治疗后,术后采取forflox-6的化疗方案具有显著的效果,且毒副反应小,值得推广。

关 键 词:forflox-6化疗方案  晚期直肠癌  术后辅助化疗  治疗效果  毒副反应

Analysis of the Help and Prognosis of Adjuvant Chemotherapy for Advanced Rectal Cancer after Chemotherapy with forflox-6
Affiliation:(Department of Foreigners,Huidong County People's Hospital,Huizhou 516300,China)
Abstract:Objective To investigate the therapeutic effect and prognosis of advanced rectal cancer with adjuvant chemotherapy for forflox-6.Methods Sixty patients with advanced rectal cancer were randomly selected as the study subjects.The study subjects were divided into two groups,namely,30 cases in each group of the study group and the control group.Both groups were treated with surgery.The control group was treated with xelox adjuvant chemotherapy.For treatment,the study group was treated with forflox-6 adjuvant chemotherapy,and the therapeutic effects and toxic side effects during the treatment were observed.Results The total effective rate of the study group was 90.00%,which was significantly higher than the total effective rate of 63.33%in the control group(P<0.05).The study group had various side effects such as myelosuppression,liver function damage,nausea and vomiting and diarrhea during chemotherapy.The overall incidence was significantly lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion For advanced rectal cancer,after surgery,the treatment of forflox-6 has a significant effect,and the toxicity and side effects are small,which is worthy of promotion.
Keywords:forflox-6 Chemotherapy Regimen  Advanced Rectal Cancer  Postoperative Adjuvant Chemotherapy  Therapeutic Effect  Toxic Side Effects
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