高负压引流治疗乳腺癌术后皮瓣下积液感染的效果观察

目的探讨高负压引流治疗乳腺癌术后皮瓣下积液感染的效果。方法选择2014年4月-2019年2月到我院进行治疗的68例乳腺癌术后皮瓣下积液感染患者作为研究对象,按随机数表法分为对照组34例和观察组34例,对照组采用常规中心负压引流法,观察组患者接受高负压引流治疗,观察两组换药次数、平均拔管时间、伤口愈合时间以及抗生素用量、血清C-反应蛋白(CRP),肿瘤坏死因子-α(TNF-α)及白细胞计数(WBC)情况。结果观察组换药次数以及抗生素用量均明显较对照组更少,平均拔管时间、伤口愈合时间明显较对照组缩短(P<0.05);观察组CRP、TNF-α以及WBC水平较对照组均明显降低(P<0.05)。结论运用高负压引流治疗乳腺癌术后皮瓣下积液感染能够有效缩短患者治疗时间、减少抗生素的使用量,促进患者恢复。

Curative Effect of High Negative Pressure Drainage on Effusion Infection Under Flap After Breast Cancer Surgery

Objective To investigate the curative effect of high negative pressure drainage on effusion infection under flap after breast cancer surgery. Methods A total of68 patients with effusion infection under flap after breast cancer surgery who were treated in the hospital from April 2014 to February 2019 were enrolled. The random number table method was performed to dividedthem intocontrol group and observation group, 34 cases in each group. The control group was given routine central negative pressuredrainage, while observation group was given high negative pressuredrainage. The number of dressing change, average extubation time, wound healing time, antibiotic dosage, serum C-reactive protein(CRP), tumor necrosis factor-α(TNF-α) and white blood cell count(WBC) in both groups were observed. Results The number of dressing change and antibiotics dosagein observation group were significantly less than those in control group, average extubation time and wound healing time were significantly shorter than those in control group(P<0.05). CRP, TNF-αand WBC levels in observation group were significantly lower than those in control group(P<0.05). Conclusion The application of high negative pressure drainage in effusion infection under flap after breast cancer surgerycan effectively shorten treatment time, reduceantibiotics dosage, and promote recovery of patients.