晚期宫颈癌病人营养现状及早期营养支持治疗效果分析

目的探讨晚期宫颈癌病人营养现状及早期营养支持治疗效果。方法对我院2015年12月-2017年12月收治的宫颈癌晚期患者170例采用NRS2002量表进行营养风险筛查,根据评估结果将有营养不良风险的118例患者按随机抽签法分为观察组(n=59)和对照组(n=59),对照组给予常规饮食支持,观察组给予早期营养支持治疗,均治疗4周后比较两组患者的营养指标水平改善情况,采用QLQ-C30量表评价两组患者治疗前后的生存质量。结果宫颈癌晚期患者营养风险发生率为69.41%;治疗后观察组患者BMI、体重、肱二头肌皮褶厚度、总蛋白、白蛋白及血红蛋白水平均显著改善,且均显著优于对照组(均P<0.05);治疗后观察组躯体、角色、情绪、社会功能评分及总体健康状况评分较治疗前均显著升高,观察组疲乏、恶心呕吐、睡眠障碍、食欲减退、便秘症状评分较治疗前均显著降低,且观察组均显著优于对照组(均P<0.05)。结论晚期宫颈癌患者营养风险发生率较高,早期营养支持治疗可有效纠正其营养状态,改善其生存质量。

Nutritional Status of Patients with Advanced Cervical Cancer and Analysis of Treatment Effects of Early Nutritional Support

Objective To explore the nutritional status of patients with advanced cervical cancer and treatment effects of early nutritional support. Methods A total of 170 patients with advanced cervical cancer who were admitted to our hospital from December 2015 to December 2017 were given nutritional risk screening by NRS2002 scale. According to the assessment results, 118 patients with malnutrition risk were divided into observation group(n=59) and control group(n=59) by method of random sampling. Control group was given routine dietary support, and observation group was given early nutritional support. After 4 w of treatment, the improvement of nutritional indexes levels was compared between the two groups, and QLQ-C30 was used to evaluate the quality of life in the two groups before and after treatment. Results The incidence rate of nutritional risk was 69.41% in patients with advanced cervical cancer. After treatment, the BMI, body weight, biceps skinfold thickness and levels of total protein, albumin and hemoglobin were significantly improved in observation group after treatment, and were significantly better than those in control group(all P<0.05). After treatment, the scores of body function, role function, emotional function and social function and the score of overall health status in observation group were significantly increased compared with those before treatment, and the scores of fatigue, nausea and vomiting, sleep disorder, loss of appetite and constipation symptom in observation group were significantly decreased compared with those before treatment, and the scores in observation group were significantly better than those in control group(all P<0.05). Conclusion The incidence rate of nutritional risk is high in patients with advanced cervical cancer. Early nutritional support treatment can effectively correct their nutritional status and improve the quality of life.