| 肿瘤坏死因子相关凋亡诱导配体及其在脑缺血中的作用 |
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| 引用本文： | 徐阳,赵学廉,吴雪松,储照虎. 肿瘤坏死因子相关凋亡诱导配体及其在脑缺血中的作用[J]. 国际脑血管病杂志, 2011, 19(12): 940-943. DOI: 10.3760/cma.j.issn.1673-4165.2011.12.013 |
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| 作者姓名： | 徐阳 赵学廉 吴雪松 储照虎 |
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| 作者单位： | 皖南医学院弋矶山医院神经内科, 芜湖,241001 |
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| 摘 要： | 肿瘤坏死因子相关凋亡诱导配体(tumor necrosis factor-related apoptosis-inducing ligand,TRAIL)在缺血等病理状态下被诱导,并介导脑缺血后的神经元凋亡.了解TRAIL在缺血脑组织中的上调机制,有望开发出新的卒中治疗方法.
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| 关 键 词： | 肿瘤坏死因子相关凋亡诱导配体 受体,肿瘤坏死因子相关凋亡诱导配体 脑缺血 动脉粥样硬化 细胞凋亡 |
Tumor necrosis factor-related apoptosis-inducing ligand and its roles in cerebral ischemia |
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| XU Yang,ZHAO Xue-lian,Wu Xue-song,CHU Zhao-hu. Tumor necrosis factor-related apoptosis-inducing ligand and its roles in cerebral ischemia[J]. International Journal of Cerebrovascular Diseases, 2011, 19(12): 940-943. DOI: 10.3760/cma.j.issn.1673-4165.2011.12.013 |
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| Authors: | XU Yang ZHAO Xue-lian Wu Xue-song CHU Zhao-hu |
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| Abstract: | Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) can be induced in ischemia and other pathological states and mediate neuronal apoptosis after cerebral ischemia.Understanding the upregulation mechanism of TRAIL in ischemic brain tissue is promising to develop new treatment for stroke. |
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| Keywords: | TNF-related apoptosis-inducing ligand Receptors,TNF-related apoptosisinducing ligand Brain ischemia Atherosclerosis Apoptosis |
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