| 手术逆转压力负荷性左心室肥厚的实验研究 |
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| 引用本文： | 冯耀光,李峰,王元星,贺大璞. 手术逆转压力负荷性左心室肥厚的实验研究[J]. 国际病理科学与临床杂志, 2011, 31(6): 461-466. DOI: 10.3969/j.issn.1673-2588.2011.12.001 |
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| 作者姓名： | 冯耀光 李峰 王元星 贺大璞 |
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| 作者单位： | 南华大学附属第一医院胸心外科,湖南衡阳,421001 |
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| 摘 要： | 目的:探讨外科手术逆转压力负荷性左心室肥厚的有效性.方法:75只SD大鼠随机分为正常组(n=15)和肥厚组(n=60),后者行腹主动脉缩窄术造成左心室肥厚；肥厚组存活大鼠再随机分为实验组(n=26)和对照组(n=20),实验组大鼠再次手术解除腹主动脉的缩窄,术后每周取血液标本检测血管紧张素Ⅱ(angiotensinⅡ,...
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| 关 键 词： | 外科手术 逆转 肥厚 主动脉 狭窄 |
Experimental study on reversing pressure overload-induced left ventricular hypertrophy by surgery |
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| FENG Yaoguang,LI Feng,WANG Yuanxing,HE Dapu. Experimental study on reversing pressure overload-induced left ventricular hypertrophy by surgery[J]. Journal of International Pathology and Clinical Medicine, 2011, 31(6): 461-466. DOI: 10.3969/j.issn.1673-2588.2011.12.001 |
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| Authors: | FENG Yaoguang LI Feng WANG Yuanxing HE Dapu |
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| Affiliation: | FENG Yaoguang,LI Feng,WANG Yuanxing,HE Dapu (Department of Cardiothoracic Surgery,First Affiliated Hospital of University of South China,Hengyang Hunan 421001,China) |
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| Abstract: | Objective To explore the effect of surgery on reversing pressure overload-induced left ventricular hypertrophy. Methods Seventy-five SD rats were randomly divided into a normal group and a myocardial hypertrophy group,which were induced by banding the abdominal aorta.The survived rats in myocardial hypertrophy group were further divided into a control group and a experimental group.The rats in experimental group were subjected to relieve abdominal aorta banding.The blood samples were taken for the measureme... |
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| Keywords: | surgical operation hypertrophy aorta stenosis reverse |
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