急性胰腺炎的多层螺旋CT灌注成像研究

目的评价急性胰腺炎的多层螺旋CT(MSCT)灌注成像特点。方法应用16层螺旋CT对胰腺正常者44例,急性胰腺炎患者23例进行灌注扫描,使用AW4.1工作站perfusion3软件包进行图像处理,得到血流量(BF)、血容量(BV)、平均通过时间(MTT)和表面通透性(PS)等参数值。结果正常组BF、BV、MTT、PS值分别为:(174.77±75.62)ml/(100g·min)、(15.62±3.39)ml/100g、(7.45±2.82)s、(14.01±9.20)ml/(100g·min);急性胰腺炎组分别为:(101.50±49.50)ml/(100g·min)、(8.86±3.08)ml/100g、(8.31±3.06)s、(21.61±9.38)ml/(100g·min)。两组之间的BF、BV、PS值之间的差别有统计学意义(P<0.01),MTT值的差别没有统计学意义(P>0.05)。结论急性胰腺炎的血液灌注量减少,MSCT灌注成像对急性胰腺炎的诊断有一定的临床应用价值。

Study of acute pancreatitis with multisl ice CT perfusion imaging

Objective To study the features of multi-slice CT (MSCT) perfusion images in acute pancreatitis (AP). Meth-ods Forty-four cases of normal pancreas and 23 cases of AP underwent CT perfusion imaging. The mean values of blood flow(BF), blood volume (BV) , mean transit time (MTT) and permeability surface ( PS) were measured on AW 4. 1 work-station with perfusion 3 software package.Results The mean values of normal pancreas group were : BF (174.77 ±75. 62)ml/(100g·min) , BV (15. 62 ±3. 39) ml/100 g , MTT (7.45±2.82)s ,PS(14.01±9.20)ml/(100g·min).The valuesin AP group were : BF (101. 50 ±49.50)ml/(100g·min),BV (8.86±3.08) ml/ 100g, MTT (8.31±3.06)s , PS(21.61±9.38)ml/(100 g ·min) . There was statistically significance (P<0.01)between the two groups besides MTT (P>0.05).Conclusion Blood perfusion valuedecreased significantly in AP. CT perfusion imaging provided more information of AP for clinical diagnosis.