肝细胞癌合并门静脉癌栓的外科治疗

目的探讨肝细胞癌伴门静脉癌栓的外科治疗方法。方法回顾性分析我院2000年1月～2006年12月收治的肝细胞癌合并门静脉癌栓63例的临床资料。根据治疗方式的不同分为综合治疗组(21例)、门静脉取栓组(12例)和姑息治疗组(30例),比较各组的生存期。结果综合治疗组、门静脉取栓组和姑息治疗组的中位生存时间分别为12.7个月、7.4个月和4.3个月,有显著性差异(P<0.05)。综合治疗组、门静脉取栓组的疗效均明显优于姑息治疗组。结论对于能耐受手术的门静脉癌栓病人应积极行肝癌切除术并术中取栓治疗。

Surgical treatment of hepatocellular carcinoma with portal vein tumor thrombus

Objective To study the value of surgical treatment for hepatocellular carcinoma(HCC)with portal vein tumor thrombus(PVTT).Methods From Jan.2000 to Dec.2006,63 cases of HCC with portal vein tumor thrombus undergoing hepatectomy and portal vein tumor thrombi extraction were retrospectively reviewed,and divided into three groups according to the different treatments:integrated treatment group(n=21),PVTT treatment group(n=12),alleviative group(n=30).Results The median survival time in integrated treatment group,PVTT treatment group and alleviative group was 12.7,7.4 and 4.3 months respectively with the difference being significant among the three groups(P<0.05).Conclusion Surgical intervention is effective in the treatment of HCC with PVTT.