| HPLC法测定清胆胶囊中黄芩苷的含量 |
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| 引用本文： | 陈树和,尹玲,黄传俊. HPLC法测定清胆胶囊中黄芩苷的含量[J]. 中国药师, 2009, 12(9): 1201-1202 |
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| 作者姓名： | 陈树和 尹玲 黄传俊 |
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| 作者单位： | 湖北省中医院药事部,武汉,430061 |
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| 摘 要： | 目的：建立以高效液相色谱法测定清胆胶囊中黄芩苷含量的方法。方法：色谱柱Agilent HC-C18（250mm×4．6mm，5μm），流动相为甲醇-0．2％磷酸（50：50），检测波长为278nm。结果：黄苓苷进样量在0．50～2．50μg范围内与峰面积积分值呈良好线性关系（r=0．9995）；平均回收率为96．13％，RSD=1．20％（n=6）。结论：本方法简便，准确可靠，可用于清胆胶囊的质量控制。
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| 关 键 词： | 清胆胶囊 黄芩苷 HPLC法 含量测定 |
Determination the Content of Baicalin in Qingdan Capsules by HPLC |
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| Chen Shuhe,Yin Ling,Huang Chuanjun. Determination the Content of Baicalin in Qingdan Capsules by HPLC[J]. China Pharmacist, 2009, 12(9): 1201-1202 |
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| Authors: | Chen Shuhe Yin Ling Huang Chuanjun |
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| Affiliation: | ( Department of Pharmaceutical Affairs, Traditional Chinese Medicine Hospital of Hubei Province, Wuhan 430061, China) |
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| Abstract: | Objective： To establish an HPLC method to determine the content of baicalin in qingdan capsules. Method： Agilent HC-C18 （250mm ×4.6mm,5μm） was used as chromatographic column, and the mobile phrase was consisted of methanol -0.2% phosphoric acid （50： 50） with a detection wavelength of 278 nm. Result： The linear range of Baicalin was 0.50 -2. 50μg（r = 0.999 5 ）. The average recovery of baicalin was 96.13% and RSD was 1.20% （ n = 6）. Conclusion： The method is sampe, accurate and reliable, and can be used for the quality control of qingdan capsules. |
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| Keywords: | Qingdan capsules Baicalin HPLC Determination |
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