| 克班宁的抗心律失常作用 |
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| 引用本文： | 淤泽溥,马云淑,赵子仙,王方材. 克班宁的抗心律失常作用[J]. 中国中药杂志, 1992, 17(11): 685-687 |
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| 作者姓名： | 淤泽溥 马云淑 赵子仙 王方材 |
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| 作者单位： | 云南中医学院中药系,昆明650011 |
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| 摘 要： | 静注克班宁5mg/kg能使BaCl2引起的大鼠心律失常迅速转为窦性节律;可明显提高乌头碱引起大鼠室颤和死亡的用量;能减少CaCl2所致大鼠和氯仿所致小鼠的室颤发生率和死亡率;但不能提高豚鼠心脏哇巴因中毒的耐受量。
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| 关 键 词： | 克班宁 抗心律失常 |
| 收稿时间： | 1991-05-24 |
Antiarrhythmic Effects of Crebanine |
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| Yu Zepu,Ma Yunshu,Zhao Zixian and Wang Fangcai. Antiarrhythmic Effects of Crebanine[J]. China Journal of Chinese Materia Medica, 1992, 17(11): 685-687 |
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| Authors: | Yu Zepu Ma Yunshu Zhao Zixian Wang Fangcai |
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| Affiliation: | Department of Traditional Chinese Pharmacy, Yunnan College of TCM, Kunming. |
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| Abstract: | Crebanine (Cre) iv 5mg/kg could eonvert BaCl2-induced arrhythmia into sinus rhythm in rats, and could significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata. The drug could also decrease the incidence of VF and CA by CaCl2 in rats and by chloroform in mice, but had no proteetive effects on ouahain-indueed arrhythmias in guinea pigs. |
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| Keywords: | crebanine antiarrhythmia |
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