|
|||||
|
|
| 光学相干断层扫描技术在原发性开角型青光眼早期诊断中的应用 | |
| 引用本文： | 海鸥,郭莉,郭春霞,崔志利.光学相干断层扫描技术在原发性开角型青光眼早期诊断中的应用[J].国际眼科杂志,2018,18(5):909-911. |
| 作者姓名： | 海鸥 郭莉 郭春霞 崔志利 |
| 作者单位： | 中国陕西省西安市,中国人民解放军第四五一医院眼科,中国陕西省西安市,空军工程大学信息与导航学院门诊部,中国陕西省西安市,空军工程大学信息与导航学院门诊部,中国陕西省西安市,空军军医大学西京医院眼科 |
| 摘 要： | 目的：探讨利用光学相干断层扫描技术(optical coherence tomography， OCT)测量视乳头旁视网膜神经纤维层(retinal nerve fiber layer， RNFL)厚度、视盘形态和黄斑区视网膜厚度在原发性开角型青光眼(primary open angle glaucoma， POAG)早期诊断中的应用价值。 方法：选取2016-01/2017-06本院收治的POAG 患者65例85眼作为研究组， 随机选取同期在本院进行身体检查的健康者52例78眼作为对照组，采用OCT测量视乳头旁RNFL厚度、黄斑区视网膜厚度和视盘参数包括杯/盘比(C/D)、视杯面积(cup area， CA)、视杯容积(cup volume， CV)、视盘面积(disc area， DA)、盘沿面积(rim area， RA)和盘沿容积(rim volume， RV)，并对检测结果进行比较分析。 结果：研究组视乳头旁RNFL厚度在上方、下方、颞侧、鼻侧和均值均明显小于对照组，差异有统计学意义(P<0.001)； 研究组CA、CV、C/D明显高于正常对照组，差异有统计学意义(P<0.001)，而DA、RV明显小于正常对照组，差异有统计学意义(P<0.001)，DA则略小于正常对照组，差异无统计学意义(P>0.05)。研究组黄斑区视网膜厚度在上方、下方、颞侧、鼻侧均明显小于对照组，差异有统计学意义(P<0.001)。 结论：OCT能够定量客观检测RNFL厚度、黄斑区视网膜厚度和视盘参数，这有助于POAG的早期诊断。 |
| 关 键 词： | 光学相干断层扫描成像术 原发性开角型青光眼 视网膜神经纤维层厚度 视盘参数 黄斑区视网膜厚度 |
| 收稿时间： | 2018/1/25 0:00:00 |
| 修稿时间： | 2018/3/30 0:00:00 |
Optical coherence tomography in diagnosis of early primary open angle glaucoma |
|
| Ou Hai,Li Guo,Chun-Xia Guo and Zhi-Li Cui.Optical coherence tomography in diagnosis of early primary open angle glaucoma[J].International Journal of Ophthalmology,2018,18(5):909-911. | |
| Authors: | Ou Hai Li Guo Chun-Xia Guo and Zhi-Li Cui |
| Institution: | Department of Ophthalmology, the 451th Hospital of Chinese PLA, Xi''an 710030, Shaanxi Province, China,Outpatients Department, School of Information and Navigation, Air force Engineering University, Xi''an 710077, Shaanxi Province, China,Outpatients Department, School of Information and Navigation, Air force Engineering University, Xi''an 710077, Shaanxi Province, China and Department of Ophthalmology, Xijing Hospital, Medical University of the Air Force, Xi''an 710032, Shaanxi Province, China |
| Abstract: | AIM: To evaluate the clinical value of retinal nerve fiber layer(RNFL)thickness, optic disc parameters and macular thickness by optical coherence tomography(OCT)in early diagnosis of primary open angle glaucoma(POAG). METHODS: Sixty-five patients(eighty-five eyes)were selected as a study group and fifty-two normal people(seventy-eight eyes)were selected as a control group. The retinal nerve fiber layer thickness, optic disc parameters, including cup/disc(C/D)rate, cup area(CA), cup volume(CV), disc area(DA), rim area(RA)and rim volume(RV), and macular thickness were detected by Cirrus HD-OCT. The data were compared and analyzed. RESULTS: The retinal nerve fiber layer thickness of superior, inferior, temple, nasal and average in the study group were all significantly thinner than those of the control group(P<0.001). The cup area, cup volume and cup/disc ratio in the study group were significantly higher than those of the control group(P<0.001); while the rim area and rim volume in the study group were significantly lower than those of the control group(P<0.001). But the disc area was not significantly different between two groups(P>0.05). The macular thickness of superior, inferior, temple and nasal in the study group were all significantly thinner than those of the control group(P<0.001). CONCLUSION: OCT can detect the change of retinal nerve fiber layer thickness, optic disc parameters and macular thickness, it is helpful for early diagnosis of POAG. |
| Keywords: | optical coherence tomography primary open angle glaucoma retinal nerve fiber layer thickness optic disc parameters macular thickness |
| 点击此处可从《国际眼科杂志》浏览原始摘要信息 | |
| 点击此处可从《国际眼科杂志》下载免费的PDF全文 | |