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早期声门型喉癌微创治疗疗效回顾性分析
引用本文:徐 进,陈海兵,陈 曦,汪李琴,陈若希. 早期声门型喉癌微创治疗疗效回顾性分析[J]. 南京医科大学学报(自然科学版), 2018, 0(10): 1439-1441
作者姓名:徐 进  陈海兵  陈 曦  汪李琴  陈若希
作者单位:南京医科大学第一附属医院耳鼻喉科,江苏 南京 210029,南京医科大学第一附属医院耳鼻喉科,江苏 南京 210029,南京医科大学第一附属医院耳鼻喉科,江苏 南京 210029,南京医科大学第一附属医院耳鼻喉科,江苏 南京 210029,南京医科大学第一附属医院耳鼻喉科,江苏 南京 210029
摘    要:目的:回顾性分析支撑喉镜下微创手术治疗早期声门型喉癌的疗效。方法:159例早期声门型喉癌患者,行支撑喉镜下微创手术治疗,其中115例行低温等离子手术,44例行电刀切除,评估患者肿瘤复发率及无瘤生存率。结果:患者无出血、呼吸困难、大咯血等严重并发症。随访满2年120例中,等离子组复发率10.98%(9/82例),电刀组复发率13.16%(5/38例),差异无统计学意义(P>0.05);侵犯前联合复发率17.14%(6/35例)高于未侵犯前联合9.41%(8/85例),但差异无统计学意义。等离子组与电刀组患者4年无瘤生存率分别为85.02%和81.50%,差异无统计学意义。结论:早期声门型喉癌行等离子射频消融术安全、可靠,创伤小,能完整切除肿瘤,尽可能保留喉功能,术后复发率低。可以用于早期声门型喉癌的治疗。

关 键 词:声门型喉癌;等离子射频消融术;生存率
收稿时间:2018-04-23
修稿时间:2018-06-18

Retrospective analysis of the effect of minimally invasive treatment of early glottic laryngeal carcinoma
Affiliation:Department of Otorhinolaryngology,The Fist Affiliated Hospital,Nanjing Medical University,,,,
Abstract:Objective Retrospective analysis of the curative effect of minimally invasive surgery in the treatment of early glottic laryngeal carcinoma. Methods 159 patients with early glottic cancer, were divided into two groups: radiofrequency group with 115 patients and non-radiofrequency group with 44 patients. The recurrence rate and cancerfree survival rate of the tumor was evaluated. Results No serious complications such as bleeding, dyspnea and hemoptysis was occurred. There was no statistically significant difference in the recurrence rate with or without anterior commissure involved. Four-year cancerfree survival rates were 85.02% and 81.50% for radiofrequency group and non-radiofrequency group, and the difference was not statistically significant. Conclusion Radiofrequency ablation is safe and reliable in early glottic laryngeal carcinoma. It can remove the tumor completely and retain the function of larynx as far as possible, and the recurrence rate is low.
Keywords:glottic laryngeal carcinoma   early   radiofrequency ablation   Survival rate
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