| 新生儿常见超说明书用药的合理性探讨 |
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| 引用本文： | 侯齐书,叶继锋,朱光辉,王增寿. 新生儿常见超说明书用药的合理性探讨[J]. 中国现代应用药学, 2018, 35(5): 760-763 |
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| 作者姓名： | 侯齐书 叶继锋 朱光辉 王增寿 |
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| 作者单位： | 温州医科大学附属第二医院、育英儿童医院, 浙江 温州 325000,温州医科大学附属第二医院、育英儿童医院, 浙江 温州 325000,温州医科大学附属第二医院、育英儿童医院, 浙江 温州 325000,温州医科大学附属第二医院、育英儿童医院, 浙江 温州 325000 |
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| 基金项目： | 温州市公益性科技计划项目（Y20170698） |
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| 摘 要： | 目的 分析新生儿科常见超说明书用药的合理性，为保障新生儿安全合理用药提供依据。方法 收集2016年8月-2017年7月新生儿科住院患儿用药医嘱，对其中常见的超说明书用药情况进行合理性分析与评价。结果 超说明书用药的存在不可避免，应根据循证医学证据强度对超说明书用药合理性进行评价。结论 临床药师应参与药物超说明书用药的规范化管理，积极寻找医学证据，为临床医师提供科学合理的用药参考。
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| 关 键 词： | 新生儿 超说明书用药 用药合理性 |
| 收稿时间： | 2017-10-24 |
| 修稿时间： | 2018-01-12 |
Discussion on the Rationality of Common Off-label Use in Neonates |
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| HOU Qishu,YE Jifeng,ZHU Guanghui and WANG Zengshou. Discussion on the Rationality of Common Off-label Use in Neonates[J]. The Chinese Journal of Modern Applied Pharmacy, 2018, 35(5): 760-763 |
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| Authors: | HOU Qishu YE Jifeng ZHU Guanghui WANG Zengshou |
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| Affiliation: | The 2nd Affiliated Hospital & Yuying Children''s Hospital of Wenzhou Medical University, Wenzhou 325000, China,The 2nd Affiliated Hospital & Yuying Children''s Hospital of Wenzhou Medical University, Wenzhou 325000, China,The 2nd Affiliated Hospital & Yuying Children''s Hospital of Wenzhou Medical University, Wenzhou 325000, China and The 2nd Affiliated Hospital & Yuying Children''s Hospital of Wenzhou Medical University, Wenzhou 325000, China |
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| Abstract: | OBJECTIVE To discuss the rationality of common off-label use in neonates, and to provide a reference for neonates safety and rational administration.METHODS Medication orders in neonatal department were collected from August 2016 to July 2017, and the rationality of common off-label use evaluated.RESULTS Off-label use was inevitably, which should be evaluated on the basis of analysis on the presence of evidence-based.CONCLUSION Clinical pharmacists shall participate in the standard management of off-label use, seek medical evidence actively, and provide scientific and reasonable suggestions to clinicians. |
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| Keywords: | neonate off-label use rationality of administration |
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