| 益母草化学成分与药理作用研究进展 |
| |
| 引用本文： | 乔晶晶,吴啟南,薛敏,王倩,许一鸣,吴达维.益母草化学成分与药理作用研究进展[J].中草药,2018,49(23):5691-5704. |
| |
| 作者姓名： | 乔晶晶 吴啟南 薛敏 王倩 许一鸣 吴达维 |
| |
| 作者单位： | 南京中医药大学药学院, 江苏省中药资源产业化过程协同创新中心, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学药学院, 江苏省中药资源产业化过程协同创新中心, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学药学院, 江苏省中药资源产业化过程协同创新中心, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学药学院, 江苏省中药资源产业化过程协同创新中心, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学药学院, 江苏省中药资源产业化过程协同创新中心, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学药学院, 江苏省中药资源产业化过程协同创新中心, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023 |
| |
| 摘 要： | 益母草Leonurus japonicas为临床常用大宗药材,具有活血调经、利水消肿、清热解毒的功效,常用于血滞经闭、痛经、经行不畅、水肿、小便不畅等病症。目前从益母草中已分离得到120余个化合物,包括生物碱、二萜、黄酮、苯乙醇苷、苯丙素、香豆素、三萜、有机酸、挥发油等类成分。益母草及其所含化学成分对子宫、心血管系统、血液、肾脏等有不同程度的作用,查阅近20年来的国内外文献,对益母草中已分离得到的化学成分与药理作用进行归纳总结,以期为益母草今后的研究开发提供参考。
|
| 关 键 词： | 益母草 生物碱 二萜 黄酮 苯乙醇苷 苯丙素 香豆素 三萜 有机酸 挥发油 抗氧化 抗炎 镇痛 |
| 收稿时间： | 2018/4/20 0:00:00 |
Research progress on chemical components and pharmacological effects of Leonurus japonicas |
| |
| QIAO Jing-jing,WU Qi-nan,XUE Min,WANG Qian,XU Yi-ming and WU Da-wei.Research progress on chemical components and pharmacological effects of Leonurus japonicas[J].Chinese Traditional and Herbal Drugs,2018,49(23):5691-5704. |
| |
| Authors: | QIAO Jing-jing WU Qi-nan XUE Min WANG Qian XU Yi-ming and WU Da-wei |
| |
| Institution: | Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China,Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China,Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China,Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China,Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China and Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China |
| |
| Abstract: | Leonurus japonicas is a common clinical medicine, with the effect of activating blood circulation and regulating menstruation, inducing diuresis to alleviate edema, and clearing heat and detoxification. It has been used to treat menoxenia, dysmenorrhea, amenorrhea, lochia, edema of the body, oliguresis, sores, ulcerations, and other diseases in human. Recently, more than 120 compounds, including alkaloids, diterpenes, flavonoids, phenylethanoid glycosides, phenylpropanoids, coumarins, triterpene, organic acid, volatile oils and so on, have been isolated from L. japonicas. L. japonicas and its active ingredients have pharmacological effects in uterus, cardiovascular system, blood, and kidney. In this review, we summarized domestic and foreign literatures about chemical composition and pharmacological activity of L. japonicas in recent 20 years, in the hope of providing reference for further studies of L. japonicas. |
| |
| Keywords: | Leonurus japonicas Houtt alkaloids diterpenes flavonoids phenylethanoid glycosides phenylpropanoids coumarins triterpene organic acid volatile oils anti-oxidant activity anti-inflammatory activity analgesic effect |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中草药》浏览原始摘要信息 |
| 点击此处可从《中草药》下载免费的PDF全文 |
|
