2014至2016年医院抗肿瘤药物临床应用分析

目的 了解近年某三甲医院抗肿瘤药物应用情况及趋势,为临床合理用药提供参考。 方法 采用限定日剂量(DDD),对医院抗肿瘤药物用药金额、用药频度(DDDs)、限定日费用(DDC)和年均复合增长率(CAGR)等进行回顾性分析。 结果2014至2016年医院抗肿瘤药用药金额增长较快,用药金额占比逐年上升；用药金额及DDDs排序前10位中多数品种为抗肿瘤中成药,艾迪注射液和鸦胆子油乳注射液的用药金额大幅上升占据前2位,复方斑蝥胶囊DDDs连续3年排名第一,DDDs排序靠前者DDC较低。 结论 该院抗肿瘤药物品种相对稳定,临床应用基本符合肿瘤用药特点,应同时关注效益与成本,提高合理用药水平。

Analysis on application of antineoplastic arugs in hospitals during 2014-2016

Objective To analyze the application of antineoplastic drugs in hospitals,and to provide reference for clinical rational drug use. Methods The amount of drugs,the defined daily dose system (DDDs),defined daily consumption(DDC) and the compound annual growth rate (CAGR) was analyzed retrospectively using the defined daily dose method (DDD).Results From 2014 to 2016,the hospital antitumor drugs increased rapidly.The amount of drug proportion increased year by year.Most of the top 10 varieties of DDDs were antitumor Chinese patent medicines.The amount of Addie injection and Brucea javanica oil injection increased substantially,occupying the top two.DDDs of Fufangbanmao capsules ranked first for 3 consecutive years.Conclusions The variety of antitumor drugs in our hospital is relatively stable and the clinical application is basically in accordance with the characteristics of antineoplastic drugs.