基于经典剂型科学表征的中药制剂创新策略

挖掘和表征中药经典制剂的剂型特征是中药现代制剂创新的基础。本文通过对近10年国家自然科学基金委员会（NSFC）在中药制剂学科立项情况、国内外中药制剂研究文献以及中药新药注册申报情况等大数据的梳理统计,发现中药经典制剂的研究项目大幅度缩减,中药经典剂型的市场份额逐年萎缩。“中药西制”模式下的现代制剂占有市场主导地位,但因其疗效“降格”致竞争力较弱。因此,借助国家政策推动下的经典剂型研究浪潮,加快加深中药经典制剂的研究,既有助于促进中药药剂学的学科发展、提升经典医药文化素养,也能促进经典医药非遗的保护和传承。

Innovation Strategy in the Modern Chinese Medicine Based on Scientific Representation of Classic Herbs Dosage Forms

Excavating and characterizing the dosage forms characteristics of classic Chinese medicine preparations is thebasis for the innovation of modern preparations of Chinese medicine. Through the combing statistics of the NationalNatural Science Foundation of China (NSFC) on the establishment of traditional Chinese medicine preparations, theresearch literature on Chinese medicine preparations at home and abroad, and the registration of new Chinese medicinesin the past ten years, this paper finds that the research projects of classic Chinese medicines have been greatly reduced.The market share of traditional Chinese medicine classics has shrunk year by year. The modern preparation produced inthe "preparation of traditional Chinese medicine by western medicine technology" mode dominates the market. However,because of its "degraded" effect, it is less competitive. Therefore, with the wave of classic dosage forms researchpromoted by national policies, accelerating the study of classical Chinese medicine preparations will not only promote thedevelopment of pharmaceutical discipline of traditional Chinese medicine, enhance the classic medical culture literacy,but also promote the protection and inheritance of classic medicine.