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| 抗凝与溶栓治疗对急性肺血栓栓塞症患者血气的影响 | |
| 引用本文： | 贾琦,杨媛华,董兆南.抗凝与溶栓治疗对急性肺血栓栓塞症患者血气的影响[J].中国医刊,2005,40(11):37-38. |
| 作者姓名： | 贾琦 杨媛华 董兆南 |
| 作者单位： | 1. 北京市隆福医院,呼吸内科,北京,100010 2. 首都医科大学附属北京朝阳医院-北京呼吸疾病研究所,北京,100020 3. 河北省承德市北方医院,河北,承德,067000 |
| 摘 要： | 目的对256例经过抗凝治疗与溶栓治疗的肺血栓栓塞症(PTE)患者的血气结果进行分析,探讨抗凝与溶栓治疗对PTE的血气影响.方法将256例确诊PTE患者的患者分为大面积和次大面积PTE、非大面积PTE,分别进行血气资料的分析,比较治疗前后血气变化.结果大面积PTE溶栓治疗后PaO2由溶栓前64.5mmHg上升为83.5mmHg,P(A-a)O2由61.1 mmHg下降为28.7mmHg,PaCO2由32.9mmHg上升为39.6mmHg,P值均＜0.01;非大面积PTE抗凝治疗后PaO2由抗凝前69.14mmHg上升为79.61mmHg,P(A-a)O2由36.99 mmHg下降为22.99 mmHg,PaCO2由38.20mmHg上升为40.13mmHg,P值均＜0.01.结论溶栓及抗凝治疗能有效改善PTE患者的PaO2及P(A-a)O2,且能纠正大面积PTE患者的低碳酸血症. |
| 关 键 词： | 肺血栓栓塞症 抗凝 溶栓 血气分析 |
| 文章编号： | 1008-1070(2005)11-0037-02 |
| 收稿时间： | 2005-06-07 |
| 修稿时间： | 2005-08-23 |
The effect of anticoagulant and thrombolytic therapy on arterial blood gas with acute pulmonary thromboembolism |
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| JIA qi,YANG Yuan-hua,Dong Zhao-nan.The effect of anticoagulant and thrombolytic therapy on arterial blood gas with acute pulmonary thromboembolism[J].Chinese Journal of Medicine,2005,40(11):37-38. | |
| Authors: | JIA qi YANG Yuan-hua Dong Zhao-nan |
| Institution: | 1. Beijing Longfu Hospital ,Belting 100010, China ;2. Beijing Chaoyang Hospital, Beijing 100020, China;3 Chengde North Hospital, Hebei Chengde 067000,China |
| Abstract: | Objective To evaluate the effect of anticoagulant and thrombolytic therapy on arterial blood gas with acute pulmonary embolism. Methods 256 patients with acute pulmonary embolism referred to Beijing Chaoyang Hospital between 2002 and 2004 were analyzed, and paired t-test was employed to compare arterial blood gas before and after anticoagulant and thrombolytic therapy. Results PaO_2 improved from 64.5mmHg to 83.5mmHg, while P(A-a)O_2 decreased from 61.6mmHg to 28.7mmHg, PaCO_2 from 32.9mmHg to 39.6 mmHg (P<0.01, respectively) in massive pulmonary embolism group. PaO_2 improved from 69.14mmHg to 79.61mmHg, while P(A-a)O_2 decreased from 36.99mmHg to 22.99mmHg, PaCO_2 from 38.20mmHg to 40.13mmHg (P<0.01, respectively) in non-massive pulmonary embolism group. Conclusion Anticoagulant and thrombolytic therapy can increase the PaO_2,P(A-a)O_2 and improve the PaCO_2 of acute pulmonary embolism. |
| Keywords: | pulmonary thromboembolism anticoagulant thrombolysis therapy blood gas |
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