１４例肾嗜酸细胞瘤的临床病理分析

目的　探讨肾嗜酸细胞瘤的诊断和治疗。方法　回顾分析２００６年５月至２０１０年１２月收治的１４例肾嗜酸细胞瘤患者的临床资料。结果　１４例患者术前影像学诊断提示肾癌，均缺乏临床特征；其中男女各７例，年龄４４～７７岁，平均（６０.３±９.８）岁；７例行根治性肾切除术，７例行部分切除术，肿瘤大小为１.５～７ｃｍ，平均（３.５±１.７）ｃｍ。１例失访，余１３例随访５～４８个月（平均２１.４个月），无复发及转移。结论　肾嗜酸细胞瘤是少见的肾良性肿瘤，术前根据影像学诊断难以与肾癌相鉴别，经皮穿刺活检被认为是一种安全、准确的术前诊断方法。对于肾脏小肿瘤，肾部分切除术结合术中冰冻切片依然是目前最适合的诊疗手段，密切随访同样重要。

Clinical and pathological analysis of 14 cases renal oncocytoma

Objective To investigate and improve the diagnostic and therapeutic feature of renal oncocytoma（RO）.Methods The clinical data of 14 cases of patients with RO from May 2006 to December 2010 were analyzed retrospectively.Results All the 14 cases were diagnosed as renal cell carcinoma（RCC） by radiological imaging detection.There was no specificity of the clinical presentation in all the cases.The study population comprised 7 men and 7 women,and the mean age was（60.3±9.8） years（range 44-75 years）.Seven were treated with radical nephrectomy,and 7 with partial nephrectomy.Mean tumor size was 3.5±1.7 cm（range 1.5-7cm）.One patient was lost to follow-up,and there was no recurrence or death in the remaining 13 patients who were followed-up for a mean duration of 21.4 months（range 5-48 months）.Conclusion RO is a rare kind of benign renal tumors.It is difficult to differentiate preoperatively renal oncocyma from renal carcinomas by radiological imaging techniques.Percutaneous biopsy is considered a safe and accurate method of diagnosis.Thus,nephron-sparing surgery（NSS） associated with pathological detection of frozen section is the first choice treatment,especially in patients with small tumors.Further more,follow-up is essential.