Influence of dentin pretreatment with 2.5% titanium tetrafluoride on inhibiting caries at the tooth-restoration interface in situ |
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| Institution: | 1. Departamento de Odontopediatria e Ortodontia, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil;2. Escola Politécnica da UFRJ, Laboratório de Instrumentação Nuclear, Rio de Janeiro, RJ, Brazil;3. Departamento de Morfologia, Universidade Federal da Paraíba (UFPB), João Pessoa, Brasil, Brazil;1. Department of Prosthodontics, University of Heidelberg, Heidelberg, Germany;2. Department of Prosthodontics, University of Würzburg, Würzburg, Germany;3. Department of Neurophysiology, Center of Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany;1. Department of Prosthodontics, School of Dentistry, Lebanese University, Lebanon;2. Department of Anatomy, Cell Biology and Physiology, Faculty of Medicine, American University of Beirut, Lebanon;1. Department of Periodontics and Oral Biology, School of Stomatology, China Medical University, Nanjing North St. 117, Shenyang 110002, Liaoning Province, China;2. Department of Immunology and Microbiology, Jinzhou Medical University, Jinzhou 121000, Liaoning Province, China |
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| Abstract: | ObjectiveInvestigate the effects of dentin pretreatment with 2.5% titanium tetrafluoride (TiF4) aqueous solution followed by two-step self-etching (CLE/Clearfil SE Bond) and one-step self-etching adhesive systems (SBU/Single Bond Universal) on carious lesion inhibition at the tooth-restoration interface using an in situ model.DesignSixty-four cavities at the enamel-dentin junction of dental fragments were randomly distributed according to groups (n = 16): 1) TiF4 + CLE; 2) TiF4 + SBU; 3) CLE; 4) SBU. Cavities were restored using resin composite, and placed in intraoral palatal devices used by 16 volunteers for 21 days, to induce caries formation in situ. The fragments were then ground-flat to perform Knoop microhardness tests. Nine indentations were performed on each enamel and dentin substrate, subjacent to the restoration. Analysis of variance and Tukey’s test were applied.ResultsEnamel: groups receiving TiF4 dentin pretreatment (regardless of adhesive system and tooth-restoration interface distance) presented higher hardness means at a depth of 25 μm from the outer tooth surface (p < 0.0001). Dentin: groups receiving CLE presented higher means when applying TiF4 pretreatment, whereas groups restored with SBU presented higher means without pretreatment (p = 0.0003).ConclusionsDentin pretreatment with TiF4 inhibited demineralization of the enamel interface in situ, regardless of the adhesive, and TiF4 pretreatment followed by CLE application showed higher potential for inhibiting dentin demineralization at the interface. |
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| Keywords: | Adhesive system Microhardness Titanium tetrafluoride |
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