The effect of magnesium hydroxide-containing dentifrice using an extrinsic and intrinsic erosion cycling model |
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| Institution: | 1. Department of Clinical Dentistry, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Rua Monsenhor Furtado, s/nº, Fortaleza, CE, Brazil;2. Department of Restorative Dentistry, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 Cidade Universitária, São Paulo, SP, Brazil;3. Department of Restorative Dentistry, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Rua Monsenhor Furtado, s/nº, Fortaleza, CE, Brazil;1. Department of Conservative Dentistry, Faculty of Dentistry, University of Jordan, Amman, Jordan;2. Division of Cariology and Restorative Dentistry, São Leopoldo Mandic Institute and Dental Research Center, Campinas, SP, Brazil;3. Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN, USA;4. Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA;5. Erosive Tooth Wear Laboratory Supervisor, Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, IN, USA;1. School of Dentistry, The University of Adelaide, Adelaide SA 5005, Australia;2. Mawson Institute, University of South Australia, Mawson Lakes SA 5095, Australia;3. School of Dentistry, Queen Mary University of London, London E1 4NS, UK |
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| Abstract: | ObjectiveTo evaluate, in vitro, the effect of Mg(OH)2 dentifrice, and the influence of the number of experimental days, on the extrinsic (citric acid –CA) and intrinsic (hydrochloric acid –HCl) enamel erosion models.DesignHuman enamel slabs were selected according to surface hardness and randomly assigned to 3 groups (n = 9) as follows: non-fluoridated (negative control), NaF (1450 ppm F- positive control) and Mg(OH)2 (2%) dentifrices. The slabs were daily submitted to a 2-h period of pellicle formation and, over a period of 5 days, submitted to cycles (3×/day) of erosive challenge (CA 0.05 M, pH = 3.75 or HCl 0.01 M, pH = 2 for 30 s), treatment (1 min −1:3 w/w of dentifrice/distilled water) and remineralization (artificial saliva/120 min). Enamel changes were determined by surface hardness loss (SHL) for each day and mechanical profilometry analysis. Data were analyzed by two-way ANOVA followed by Tukey’s test to % SHL and one-way ANOVA to profilometry (p < 0.05).ResultsThe number of experimental days influenced the erosion process for the two types of erosion models (p < 0.001). Mg(OH)2-containing dentifrices were effective in reducing enamel extrinsic acid erosion as determined by % SHL (p < 0.001) when compared to the control group, being better than positive control (p < 0.001); however, the dentifrices were not effective for the intrinsic model (p = 0.295). With regards to surface wear, no statistically significant differences were found among the groups for CA (p = 0.225) and HCl (p = 0.526).ConclusionThe findings suggest that Mg(OH)2 dentifrices might protect enamel against slight erosion, but protection was not effective for stronger acid erosion. |
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| Keywords: | Magnesium hydroxide Toothpastes Hydrochloric acid Sodium fluoride Citric acid |
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