Osteoarticular manifestations in sickle-cell disorders |
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| Authors: | Phaedon Kaklamanis |
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| Affiliation: | (1) First Department of Internal Medicine, University of Athens, School of Medicine, Laikon General Hospital, 17, Aghiou Thoma (Goudi), 115 27 Athens, Greece |
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| Abstract: | Summary The osteoarticular manifestations of the main sickling disorders (homozygous sickle cell-HbSS anaemia-, double heterozygous-HbS- thalassaemia, double heterozygous HbS-C disease and sickle cell-trait) are reviewed; They may be grouped into 3 main categories: vaso-occlusive, infective and metabolic. The pathophysiology and pathogenesis as well as the treatment are discussed. |
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| Keywords: | Sickle-Cell Osteoarticular Manifestations |
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